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[Dr. Koala 成分小學堂] 果酸(AHA) - 四大換膚功效

7月 26 2017

[Dr. Koala 成分小學堂] 果酸(AHA) - 四大換膚功效

[Dr. Koala 成分小學堂] 果酸(AHA) - 四大換膚功效

果酸(AHA)是什麼?

果酸(α-羥基酸, Alpha-hydroxy acid, 縮寫AHA),作為羧酸的一種,不但是有機酸,更是一種能去角質達致換膚效果的成分。常用於護膚品的果酸有甘醇酸(Glycolic Acid)、乳酸(Latic Acid)、蘋果酸(Malic Acid)、檸檬酸(Citric Acid)、及酒石酸(Tartaric Acid) ,主要由天然的食物提取,例如甘蔗、蘋果、牛奶、檸檬等等。

其中又以甘醇酸(Glycolic Acid)最有效,因為粒子結構最細小(分子量76),有較高生物利用度,滲透率較高,能迅速深入皮膚底層,而乳酸則以分子量90緊隨其後。

甘蔗 甘醇酸 | Dr. Koala甘醇酸 | Dr. Koala

(左圖)圖為《科勒藥用植物》(1897), Saccharum officinarum 甘蔗。引用自https://en.wikipedia.org/wiki/Sugarcane (右圖)甘醇酸 (Glycolic Acid),C2H4O3,分子量76, pKa3.83。引用自https://en.wikipedia.org/wiki/Glycolic_acid

果酸的四大換膚功效

1. 角質剝離

經醫學研究証明果酸能有效去除皮膚老化角質細胞

複雜慎讀:其中一個由研究人員Wang 在1999年提出的機制是,果酸能有效減少皮膚表皮層的鈣離子,而鈣離子(Ca2+)作為E-鈣粘蛋白(E-Cadherins)的重要合成,降低的鈣離子濃度能令角質細胞間的粘附降低,繼而剝落。

(Wang X. A theory for the mechanism of action of the alpha-hydroxy acids applied to the skin. Med Hypotheses. 1999;53(5):380–382.)

2. 補濕及加強彈性

玻尿酸(Hydroluronic acid) - 相信各位都有聽過,而果酸能增加皮膚玻尿酸及骨膠原生成加強皮膚水潤度及彈性

複雜慎讀:有實驗以20%甘醇酸塗上前臂皮膚,每日2次為期3個月,結果顯示無論真皮層(Dermis),抑或是表皮層(Epidermis)的玻尿酸含量都有上升有,另外骨膠原的基因表現(Collagen gene expression)亦有所上升,刺激細胞的骨膠原(Collagen)生成。

(Bernstein EF, Lee J, Brown DB, Yu R, van SE. Glycolic acid treatment increases type I collagen mRNA and hyaluronic acid content of human skin. Dermatol Surg. 2001;27(5):429–433.)

(上圖)皮膚最外層是表皮層(Epidermis),90%由角質形成細胞(Keratinocytes)組成。下層是真皮層(Dermis)。引用自https://en.wikipedia.org/wiki/Human_skin

3. 刺激細胞再生

果酸能加速表皮代謝速度,促進皮膚新生。

複雜慎讀:果酸促進角質形成細胞(Keratinocytes)分泌細胞因子,繼而加快細胞凋亡(Apoptosis),另外亦會增加 VEGF的分泌。

(Rendl M, Mayer C, Weninger W, Tschachler E. Topically applied lactic acid increases spontaneous secretion of vascular endothelial growth factor by human reconstructed epidermis. Br J Dermatol. 2001;145(1):3–9.)

4. 修復皮膚光老化

皮膚老化的問題困擾着不少人,而紫外線更是主要元兇(詳見: 抗衰老大作戰(一)──認識最大敵人)。剛剛所說果酸對皮膚的功效,正正光老化的皮膚細胞起到治療效果

 

果酸迷思 - 愈用皮膚愈薄?

使用果酸得宜,不但不會令皮膚變薄,相反還會令皮膚增厚呢!

果酸只會針對死亡的皮膚細胞或受紫外線傷害的皮膚,不會去除健康的皮膚。已有多份外國臨床研究指出,果酸會令表皮層(Epidermis)的角質細胞(Corneocytes) 剝落。

與此同時,果酸更會刺激成纖維細胞(Fibroblasts) 生產骨膠原(Collegen),令真皮層(Dermis)的細胞外基質(ECM)加厚。

(Okano Y, Abe Y, Masaki H, Santhanam U, Ichihashi M, Funasaka Y. Biological effects of glycolic acid on dermal matrix metabolism mediated by dermal fibroblasts and epidermal keratinocytes. Exp Dermatol. 2003;12(Suppl 2):57–63.)

[Dr. Koala 成分成析] 果酸(AHA)

引用自https://www.pexels.com/photo/beautiful-beautiful-woman-face-feminine-355100/

果酸換膚要注意!

1. 果酸初心者

建議第一次接觸果酸護膚品的朋友先做一個小Patch test,把低度的果酸護膚品塗在耳背等15分鐘,看看有沒有果酸過敏的情況。沒有果酸過敏的話,由低濃度開始使用,再慢慢調高至適合自己的濃度。另外,亦要避免塗在眼部附近,以免果酸進入眼睛造成傷害,畢竟,要靚不用搏命。

2. 輕微刺痛及皮膚微紅

使用果酸時皮膚感到輕微刺痛及微紅時,不必驚訝,這是由於甘醇酸等果酸分子量小,很快滲入皮膚而pH值亦較低所致,八成以上使用者都會有此反應,實屬正常。剛敷上面時產生的不良感覺,一般只會持續很短時間;而敷後的皮膚微紅情況,亦很快會消散。

3. 果酸過敏

有果酸過敏的人士,不能體驗果酸換膚的功效了...切勿以身犯險唷。

4. 孕婦不能用果酸?

暫時沒有臨床報告指出孕婦不可以使用果酸,不過為安全起見懷孕期間,還是只用在面上,避免用在肚子上了。

5. 防曬要做好

使用果酸後,因為長年累月堆積在皮膚外層的老廢角質細胞都被清除掉,露出其下較嬌嫩的皮膚,對陽光的防禦力較差,容易曬傷,因此應做足防曬步驟,好好保護嫩白的新肌膚

 

要溫和地使用果酸,可選用較溫和的比例,適合每天漸進煥膚的朋友,含有果酸的產品推薦: 

1️⃣【甘醇酸+蘋果酸又溫和到日日都用得】Josh Rosebrook 亮肌爽膚水: t.ly/22kK
2️⃣【植物萃取配合檸檬酸】Green Envee 01 溫和草本潔面乳:t.ly/K8mK
3️⃣【抹茶粉+檸檬酸敷得既洗臉粉】Odacité 純美素肌抹茶潔顏粉:t.ly/iQiX

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